Fidia Aesthetic Care Hyal system ACP

Hyal-System ACP is a low molecular weight HA-based hydrogel, stabilized without involving any chemical agent, thanks to the patented ACP (Auto-Crosslinked Polymer) technology, to enable a gradual release of highly pure 200kDa HA (slow-release activity), eliciting a biostimulation response.⁷

It improves skin turgidity and elasticity, giving a rejuvenating effect to the skin⁸. As a result, the skin is firm, elastic and rejuvenated.⁶

It is also indicated for the management of hypertrophic scars (pathological or not) resulting from burns,surgical wounds and skin trauma.⁸

Composition

Auto-Crosslinked Hyaluronic Acid 200 kDa

HA Concentration

20 mg/ml – 2 %

Technology

HA A.C.P. Auto-Crosslinked Polymer
Technology^®

Injection depth

Superficial, mid or deep dermis is for soft tissue defects Intralesion derma planes for hypertrophic scars

Effect

Biostimulation / rejuvenation

Presentation

1×1 ml prefilled syringe 
1x30G 13mm, 1x30G 4mm

Before & after

BIOSTIMULATION for a progressive and sustained rejuvenation from within

Skin aging affects all layers of the skin and the reduction of the extracellular matrix (ECM), including collagen and HA, has an impact at the
dermal level.¹
The term BIOSTIMULATION indicates slow and sustained neo-collagenesis and ECM deposition after intradermal injection aimed to
optimize skin physiology and achieve an aesthetic improvement^1,2

SUBSEQUENT SESSIONS OF HA-BIOSTIMULATORY TREATMENT PROGRESSIVELY INCREASE THE ECM.¹

Expected progressive increase in ECM with subsequent sessions of crosslinked HA injections as hypothesized based on the current concept of biostimulation. Blue arrows indicate the difference in extracellular matrix content after each session¹.

Adapted from Figure 2, ref 1

LMW-HA (200 kDa) provides a microenvironment suitable to facilitate the physiological homeostasis of ECM.³

Product line

Hyal-System

BIOSTIMULATOR

HYBRID STIMULATOR

LIP FILLER

VOLUMIZING FILLER

SKINBOOSTER

Medical devices CE 0373, Class III.
Carefully read the warnings and instructions for use.

References:
1. Guida, S. et al. Journal of cosmetic dermatology vol. 23,2 (2024): 701-703. doi:10.1111/jocd.16156
2. Ceccarelli M & Curcio C. Biostimulation and Biorestructuration of the Skin, The Physiological medical Letter, Vol. 1, Jan 2010, no.2.
3. Wohlrab J, et al. J Cosmet Dermatol. 2013; 12(1):36-40.
4. Alessandrini, A et al., Aesthetic Plastic Surgery vol. 42 (2018): 520–9. doi.org/10.1007/s00266-017-1022-9
5. Costa E., Dermatol & Cosmet JOJ 6(1): JOJDC.MS.ID.555677 (2024);
6. Alessandrini, A et al. Plastic and reconstructive surgery vol. 118,2 (2006): 341-6. doi:10.1097/01.prs.0000227686.95099.58
7. Pluda, S. et al. Gels 2023, 9, 733. https://doi.org/10.3390/gels9090733
8. HYAL-SYSTEM ACP, IFU (MDD)